| VANGUARD GROUP INC |
7654482 |
7.1% |
| Palo Alto Investors LP |
5102193 |
4.7% |
| Eversept Partners, LP |
4987180 |
4.6% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
4319842 |
4.0% |
| BlackRock Finance, Inc. |
4169788 |
3.9% |
| BlackRock, Inc. |
3768875 |
3.5% |
| CITADEL ADVISORS LLC |
3101399 |
2.9% |
| MARSHALL WACE, LLP |
2580863 |
2.4% |
| GOLDMAN SACHS GROUP INC |
2290434 |
2.1% |
| MILLENNIUM MANAGEMENT LLC |
2092426 |
1.9% |
| Avidity Partners Management LP |
2018500 |
1.9% |
| JANE STREET GROUP, LLC |
1549976 |
1.4% |
| C WorldWide Group Holding A/S |
1500000 |
1.4% |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
1483727 |
1.4% |
| Opaleye Management Inc. |
1425000 |
1.3% |
| BNP PARIBAS FINANCIAL MARKETS |
1313893 |
1.2% |
| GEODE CAPITAL MANAGEMENT, LLC |
1311536 |
1.2% |
| JPMORGAN CHASE & CO |
1275859 |
1.2% |
| DEUTSCHE BANK AG\ |
1268777 |
1.2% |
| KENNEDY CAPITAL MANAGEMENT LLC |
1196792 |
1.1% |
| AlphaCentric Advisors LLC |
1125000 |
1.0% |
| GSA CAPITAL PARTNERS LLP |
983417 |
0.9% |
| BARCLAYS PLC |
873274 |
0.8% |
| NORTHERN TRUST CORP |
870167 |
0.8% |
| D. E. Shaw & Co., Inc. |
844112 |
0.8% |
| RENAISSANCE TECHNOLOGIES LLC |
756227 |
0.7% |
| AQR CAPITAL MANAGEMENT LLC |
748020 |
0.7% |
| Cubist Systematic Strategies, LLC |
568975 |
0.5% |
| SILVERARC CAPITAL MANAGEMENT, LLC |
558466 |
0.5% |
| MACQUARIE GROUP LTD |
505684 |
0.5% |
| Birchview Capital, LP |
469832 |
0.4% |
| STATE STREET CORP |
453810 |
0.4% |
| Ikarian Capital, LLC |
409355 |
0.4% |
| LOS ANGELES CAPITAL MANAGEMENT LLC |
354020 |
0.3% |
| BANK OF AMERICA CORP /DE/ |
298685 |
0.3% |
| FMR LLC |
293213 |
0.3% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
264500 |
0.2% |
| Atom Investors LP |
261847 |
0.2% |
| Centiva Capital, LP |
203600 |
0.2% |
| MORGAN STANLEY |
200008 |
0.2% |
| ACADIAN ASSET MANAGEMENT LLC |
194168 |
0.2% |
| DAFNA Capital Management LLC |
192678 |
0.2% |
| Bank of New York Mellon Corp |
166315 |
0.2% |
| EXCHANGE TRADED CONCEPTS, LLC |
162178 |
0.2% |
| CITIGROUP INC |
162027 |
0.1% |
| HRT FINANCIAL LP |
147536 |
0.1% |
| UBS Group AG |
140678 |
0.1% |
| XTX Topco Ltd |
140576 |
0.1% |
| Woodline Partners LP |
134112 |
0.1% |
| Qube Research & Technologies Ltd |
106470 |
0.1% |
| PRICE T ROWE ASSOCIATES INC /MD/ |
97100 |
0.1% |
| BOOTHBAY FUND MANAGEMENT, LLC |
91091 |
0.1% |
| State of Wyoming |
82685 |
0.1% |
| Verition Fund Management LLC |
68932 |
0.1% |
| Schonfeld Strategic Advisors LLC |
57600 |
0.1% |
| HSBC HOLDINGS PLC |
53091 |
49.1‰ |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
51000 |
47.2‰ |
| Bleakley Financial Group, LLC |
49160 |
45.5‰ |
| Simplicity Wealth,LLC |
49160 |
45.5‰ |
| Colony Group, LLC |
45930 |
42.5‰ |
| Invesco Ltd. |
40511 |
37.5‰ |
| SEI INVESTMENTS CO |
40000 |
37.0‰ |
| Baird Financial Group, Inc. |
36800 |
34.1‰ |
| Tower Research Capital LLC (TRC) |
35184 |
32.6‰ |
| KENNEDY INVESTMENT GROUP |
35000 |
32.4‰ |
| Redwood Wealth Management Group, LLC |
34030 |
31.5‰ |
| Engineers Gate Manager LP |
28700 |
26.6‰ |
| COMMONWEALTH EQUITY SERVICES, LLC |
25206 |
23.3‰ |
| Banque Cantonale Vaudoise |
25000 |
23.1‰ |
| Neuberger Berman Group LLC |
22951 |
21.2‰ |
| BALYASNY ASSET MANAGEMENT L.P. |
22562 |
20.9‰ |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC |
21941 |
20.3‰ |
| ADAR1 Capital Management, LLC |
20000 |
18.5‰ |
| ELCO Management Co., LLC |
19662 |
18.2‰ |
| RHUMBLINE ADVISERS |
16431 |
15.2‰ |
| Paloma Partners Management Co |
15435 |
14.3‰ |
| ProShare Advisors LLC |
15170 |
14.0‰ |
| Winthrop Advisory Group LLC |
15000 |
13.9‰ |
| VICTORY CAPITAL MANAGEMENT INC |
13993 |
13.0‰ |
| TWO SIGMA INVESTMENTS, LP |
13866 |
12.8‰ |
| BLB&B Advisors, LLC |
11150 |
10.3‰ |
| Snowden Capital Advisors LLC |
11000 |
10.2‰ |
| Janney Montgomery Scott LLC |
10000 |
9.3‰ |
| OSAIC HOLDINGS, INC. |
7213 |
6.7‰ |
| CWM, LLC |
6248 |
5.8‰ |
| Quent Capital, LLC |
3489 |
3.2‰ |
| PNC FINANCIAL SERVICES GROUP, INC. |
3000 |
2.8‰ |
| Founders Capital Management |
2000 |
1.9‰ |
| HARBOUR INVESTMENTS, INC. |
1300 |
1.2‰ |
| Activest Wealth Management |
1000 |
0.9‰ |
| NEW YORK STATE COMMON RETIREMENT FUND |
955 |
0.9‰ |
| SRS Capital Advisors, Inc. |
538 |
0.5‰ |
| Bruce G. Allen Investments, LLC |
507 |
0.5‰ |
| Allworth Financial LP |
500 |
0.5‰ |
| Providence Capital Advisors, LLC |
312 |
0.3‰ |
| AdvisorNet Financial, Inc |
200 |
0.2‰ |
| Financial Gravity Asset Management, Inc. |
70 |
0.1‰ |
| CIBC Private Wealth Group LLC |
50 |
< 0.1‰ |
| NISA INVESTMENT ADVISORS, LLC |
50 |
< 0.1‰ |
| West Branch Capital LLC |
48 |
< 0.1‰ |
