| BlackRock, Inc. |
11701587 |
11.5% |
| VANGUARD GROUP INC |
11636732 |
11.5% |
| BlackRock Finance, Inc. |
11237856 |
11.1% |
| BAILLIE GIFFORD & CO |
6093286 |
6.0% |
| Deep Track Capital, LP |
4500000 |
4.4% |
| Capital International Investors |
4468723 |
4.4% |
| EVENTIDE ASSET MANAGEMENT, LLC |
3760538 |
3.7% |
| Temasek Holdings (Private) Ltd |
3749102 |
3.7% |
| WELLINGTON MANAGEMENT GROUP LLP |
3508743 |
3.5% |
| CITADEL ADVISORS LLC |
3290897 |
3.2% |
| CADIAN CAPITAL MANAGEMENT, LP |
3131808 |
3.1% |
| FMR LLC |
3118623 |
3.1% |
| Parkwood LLC |
2800000 |
2.8% |
| GEODE CAPITAL MANAGEMENT, LLC |
2792534 |
2.8% |
| STATE STREET CORP |
2754977 |
2.7% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
2612777 |
2.6% |
| MILLENNIUM MANAGEMENT LLC |
2135311 |
2.1% |
| FIL Ltd |
2068481 |
2.0% |
| MORGAN STANLEY |
2021706 |
2.0% |
| FULLER & THALER ASSET MANAGEMENT, INC. |
1938515 |
1.9% |
| Point72 Asset Management, L.P. |
1815053 |
1.8% |
| Sumitomo Mitsui Trust Group, Inc. |
1464213 |
1.4% |
| NORGES BANK |
1383768 |
1.4% |
| PRICE T ROWE ASSOCIATES INC /MD/ |
1375674 |
1.4% |
| Nuveen Asset Management, LLC |
1309719 |
1.3% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
1309431 |
1.3% |
| Bank of New York Mellon Corp |
1280221 |
1.3% |
| GOLDMAN SACHS GROUP INC |
1248050 |
1.2% |
| Invesco Ltd. |
1207469 |
1.2% |
| DEUTSCHE BANK AG\ |
1073077 |
1.1% |
| FRANKLIN RESOURCES INC |
1069963 |
1.1% |
| NORTHERN TRUST CORP |
1032907 |
1.0% |
| FEDERATED HERMES, INC. |
862100 |
0.9% |
| TWO SIGMA INVESTMENTS, LP |
814523 |
0.8% |
| TWO SIGMA ADVISERS, LP |
770800 |
0.8% |
| Aristotle Atlantic Partners, LLC |
749197 |
0.7% |
| Erste Asset Management GmbH |
692600 |
0.7% |
| KINGDON CAPITAL MANAGEMENT, L.L.C. |
670200 |
0.7% |
| Pictet Asset Management Holding SA |
664108 |
0.7% |
| Eagle Health Investments LP |
626909 |
0.6% |
| Railway Pension Investments Ltd |
620878 |
0.6% |
| Trexquant Investment LP |
584914 |
0.6% |
| Blue Water Life Science Advisors, LP |
571047 |
0.6% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
541953 |
0.5% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
513283 |
0.5% |
| MPM BioImpact LLC |
500000 |
0.5% |
| JENNISON ASSOCIATES LLC |
497088 |
0.5% |
| BARCLAYS PLC |
477372 |
0.5% |
| ARK Investment Management LLC |
453590 |
0.4% |
| BNP PARIBAS FINANCIAL MARKETS |
441326 |
0.4% |
| ExodusPoint Capital Management, LP |
440379 |
0.4% |
| BANK OF AMERICA CORP /DE/ |
430500 |
0.4% |
| JPMORGAN CHASE & CO |
429385 |
0.4% |
| First Light Asset Management, LLC |
416967 |
0.4% |
| Cubist Systematic Strategies, LLC |
374130 |
0.4% |
| abrdn plc |
373591 |
0.4% |
| Candriam S.C.A. |
366145 |
0.4% |
| Mitsubishi UFJ Trust & Banking Corp |
339090 |
0.3% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
299800 |
0.3% |
| Swiss National Bank |
239400 |
0.2% |
| TUDOR INVESTMENT CORP ET AL |
239223 |
0.2% |
| JANE STREET GROUP, LLC |
203976 |
0.2% |
| FRED ALGER MANAGEMENT, LLC |
198468 |
0.2% |
| Legal & General Group Plc |
182979 |
0.2% |
| Granahan Investment Management, LLC |
181167 |
0.2% |
| CAPITAL FUND MANAGEMENT S.A. |
178219 |
0.2% |
| RHUMBLINE ADVISERS |
173298 |
0.2% |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
153809 |
0.2% |
| Exome Asset Management LLC |
147800 |
0.1% |
| Hood River Capital Management LLC |
146726 |
0.1% |
| Sicart Associates LLC |
145983 |
0.1% |
| PDT Partners, LLC |
144585 |
0.1% |
| ALLIANCEBERNSTEIN L.P. |
143720 |
0.1% |
| GUGGENHEIM CAPITAL LLC |
137811 |
0.1% |
| LAZARD ASSET MANAGEMENT LLC |
136269 |
0.1% |
| STATE OF WISCONSIN INVESTMENT BOARD |
131802 |
0.1% |
| Cerity Partners LLC |
126125 |
0.1% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
118547 |
0.1% |
| Pier Capital, LLC |
115854 |
0.1% |
| Rathbones Group PLC |
108395 |
0.1% |
| AMERICAN CENTURY COMPANIES INC |
106620 |
0.1% |
| Holocene Advisors, LP |
102944 |
0.1% |
| Casdin Capital, LLC |
100000 |
0.1% |
| Eversept Partners, LP |
99377 |
0.1% |
| Edgestream Partners, L.P. |
96513 |
0.1% |
| Engineers Gate Manager LP |
95685 |
0.1% |
| ALGERT GLOBAL LLC |
90220 |
0.1% |
| Nikko Asset Management Americas, Inc. |
88694 |
0.1% |
| Gotham Asset Management, LLC |
84748 |
0.1% |
| SWS Partners |
78857 |
0.1% |
| AMERIPRISE FINANCIAL INC |
72029 |
0.1% |
| WOLVERINE TRADING, LLC |
72000 |
0.1% |
| State of New Jersey Common Pension Fund D |
71286 |
0.1% |
| Adalta Capital Management LLC |
71023 |
0.1% |
| HSBC HOLDINGS PLC |
69746 |
0.1% |
| MetLife Investment Management, LLC |
68147 |
0.1% |
| COMERICA BANK |
68128 |
0.1% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
67180 |
0.1% |
| PRIMECAP MANAGEMENT CO/CA/ |
66176 |
0.1% |
| WELLS FARGO & COMPANY/MN |
64059 |
0.1% |
