| ARK Investment Management LLC |
11595789 |
13.0% |
| BlackRock, Inc. |
10857693 |
12.2% |
| BlackRock Finance, Inc. |
9597607 |
10.8% |
| VANGUARD GROUP INC |
9100068 |
10.2% |
| Deep Track Capital, LP |
4800000 |
5.4% |
| STATE STREET CORP |
4362780 |
4.9% |
| Nikko Asset Management Americas, Inc. |
3257689 |
3.7% |
| Sumitomo Mitsui Trust Group, Inc. |
2992663 |
3.4% |
| MORGAN STANLEY |
2337709 |
2.6% |
| FEDERATED HERMES, INC. |
2300889 |
2.6% |
| GEODE CAPITAL MANAGEMENT, LLC |
2293943 |
2.6% |
| FMR LLC |
2228418 |
2.5% |
| Casdin Capital, LLC |
2000000 |
2.2% |
| Contrarius Investment Management Ltd |
1915410 |
2.1% |
| ALLIANCEBERNSTEIN L.P. |
1782884 |
2.0% |
| DIMENSIONAL FUND ADVISORS LP |
1324561 |
1.5% |
| GOLDMAN SACHS GROUP INC |
1266602 |
1.4% |
| PRICE T ROWE ASSOCIATES INC /MD/ |
1244959 |
1.4% |
| Rokos Capital Management LLP |
1140973 |
1.3% |
| Chevy Chase Trust Holdings, LLC |
1042625 |
1.2% |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. |
1029982 |
1.2% |
| Nuveen Asset Management, LLC |
865631 |
1.0% |
| NORTHERN TRUST CORP |
835351 |
0.9% |
| TWO SIGMA INVESTMENTS, LP |
829285 |
0.9% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
789831 |
0.9% |
| WELLINGTON MANAGEMENT GROUP LLP |
781774 |
0.9% |
| TWO SIGMA ADVISERS, LP |
769917 |
0.9% |
| CITADEL ADVISORS LLC |
762680 |
0.9% |
| Pictet Asset Management Holding SA |
744032 |
0.8% |
| JPMORGAN CHASE & CO |
669105 |
0.8% |
| BANK OF AMERICA CORP /DE/ |
647734 |
0.7% |
| Discovery Value Fund |
561561 |
0.6% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
483185 |
0.5% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
452448 |
0.5% |
| MPM BioImpact LLC |
443503 |
0.5% |
| BNP PARIBAS FINANCIAL MARKETS |
438458 |
0.5% |
| Vestmark Advisory Solutions, Inc. |
375291 |
0.4% |
| Bank of New York Mellon Corp |
364306 |
0.4% |
| BALYASNY ASSET MANAGEMENT L.P. |
347483 |
0.4% |
| AMERICAN CENTURY COMPANIES INC |
330514 |
0.4% |
| CAPITAL ADVISORS INC/OK |
311045 |
0.3% |
| Temasek Holdings (Private) Ltd |
279693 |
0.3% |
| Hudson Bay Capital Management LP |
275000 |
0.3% |
| UBS Group AG |
255551 |
0.3% |
| PINNACLE ASSOCIATES LTD |
251078 |
0.3% |
| JANE STREET GROUP, LLC |
245426 |
0.3% |
| abrdn plc |
243044 |
0.3% |
| NORGES BANK |
240415 |
0.3% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
227255 |
0.3% |
| PDT Partners, LLC |
227220 |
0.3% |
| Rafferty Asset Management, LLC |
225212 |
0.3% |
| Opaleye Management Inc. |
218000 |
0.2% |
| Granahan Investment Management, LLC |
214910 |
0.2% |
| DEUTSCHE BANK AG\ |
212457 |
0.2% |
| RAYMOND JAMES & ASSOCIATES |
207295 |
0.2% |
| BARCLAYS PLC |
203373 |
0.2% |
| WELLS FARGO & COMPANY/MN |
201657 |
0.2% |
| Schonfeld Strategic Advisors LLC |
186440 |
0.2% |
| Swiss National Bank |
180300 |
0.2% |
| RHUMBLINE ADVISERS |
175335 |
0.2% |
| Neuberger Berman Group LLC |
171362 |
0.2% |
| Trexquant Investment LP |
170828 |
0.2% |
| Orchard Capital Management, LLC |
170006 |
0.2% |
| Avidity Partners Management LP |
170000 |
0.2% |
| Russell Investments Group, Ltd. |
150578 |
0.2% |
| NEOS Investment Management LLC |
149630 |
0.2% |
| SPHERA FUNDS MANAGEMENT LTD. |
139419 |
0.2% |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND |
138468 |
0.2% |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
127435 |
0.1% |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA |
117315 |
0.1% |
| LAZARD ASSET MANAGEMENT LLC |
116390 |
0.1% |
| CITIGROUP INC |
108382 |
0.1% |
| Rockefeller Capital Management L.P. |
100914 |
0.1% |
| TWINBEECH CAPITAL LP |
99952 |
0.1% |
| Invesco Ltd. |
96030 |
0.1% |
| Legal & General Group Plc |
94896 |
0.1% |
| STIFEL FINANCIAL CORP |
91508 |
0.1% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
89851 |
0.1% |
| SCHRODER INVESTMENT MANAGEMENT GROUP |
86484 |
0.1% |
| State of New Jersey Common Pension Fund D |
85826 |
0.1% |
| MILLENNIUM MANAGEMENT LLC |
75674 |
0.1% |
| ALPS ADVISORS INC |
75237 |
0.1% |
| DekaBank Deutsche Girozentrale |
75000 |
0.1% |
| McGuire Investment Group, LLC |
71994 |
0.1% |
| GSA CAPITAL PARTNERS LLP |
70355 |
0.1% |
| ALGERT GLOBAL LLC |
68372 |
0.1% |
| Elmwood Wealth Management, Inc. |
67174 |
0.1% |
| TUDOR INVESTMENT CORP ET AL |
61783 |
0.1% |
| Engineers Gate Manager LP |
61528 |
0.1% |
| GUGGENHEIM CAPITAL LLC |
61266 |
0.1% |
| BENJAMIN F. EDWARDS & COMPANY, INC. |
60913 |
0.1% |
| CAPSTONE INVESTMENT ADVISORS, LLC |
60298 |
0.1% |
| SIT INVESTMENT ASSOCIATES INC |
59900 |
0.1% |
| LPL Financial LLC |
57326 |
0.1% |
| SEVEN EIGHT CAPITAL, LP |
56413 |
0.1% |
| STATE OF WISCONSIN INVESTMENT BOARD |
56181 |
0.1% |
| MetLife Investment Management, LLC |
55696 |
0.1% |
| ENVESTNET ASSET MANAGEMENT INC |
55556 |
0.1% |
| Walleye Capital LLC |
55155 |
0.1% |
| Krilogy Financial LLC |
54673 |
0.1% |
