| ARK Investment Management LLC |
5702351 |
10.6% |
| BlackRock Finance, Inc. |
5286549 |
9.8% |
| BlackRock, Inc. |
5085767 |
9.5% |
| VANGUARD GROUP INC |
4381132 |
8.1% |
| Bellevue Group AG |
3912575 |
7.3% |
| Nikko Asset Management Americas, Inc. |
2576261 |
4.8% |
| GAGNON SECURITIES LLC |
2174167 |
4.0% |
| MILLENNIUM MANAGEMENT LLC |
2140909 |
4.0% |
| STATE STREET CORP |
2107830 |
3.9% |
| BAMCO INC /NY/ |
1876672 |
3.5% |
| D. E. Shaw & Co., Inc. |
1727890 |
3.2% |
| RENAISSANCE TECHNOLOGIES LLC |
1512700 |
2.8% |
| Sumitomo Mitsui Trust Group, Inc. |
1498018 |
2.8% |
| DIMENSIONAL FUND ADVISORS LP |
1283912 |
2.4% |
| GEODE CAPITAL MANAGEMENT, LLC |
1195583 |
2.2% |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
1178040 |
2.2% |
| FRED ALGER MANAGEMENT, LLC |
1149602 |
2.1% |
| First Eagle Investment Management, LLC |
968552 |
1.8% |
| MORGAN STANLEY |
630902 |
1.2% |
| Gagnon Advisors, LLC |
610336 |
1.1% |
| ACADIAN ASSET MANAGEMENT LLC |
610055 |
1.1% |
| BANK OF MONTREAL /CAN/ |
584589 |
1.1% |
| Blue Water Life Science Advisors, LP |
510000 |
0.9% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
485933 |
0.9% |
| GOLDMAN SACHS GROUP INC |
458330 |
0.9% |
| NORTHERN TRUST CORP |
421904 |
0.8% |
| ROYCE & ASSOCIATES LP |
392286 |
0.7% |
| Connor, Clark & Lunn Investment Management Ltd. |
390671 |
0.7% |
| BANK OF AMERICA CORP /DE/ |
250581 |
0.5% |
| OBERWEIS ASSET MANAGEMENT INC/ |
250400 |
0.5% |
| WELLINGTON MANAGEMENT GROUP LLP |
202312 |
0.4% |
| Bank of New York Mellon Corp |
193994 |
0.4% |
| AMERIPRISE FINANCIAL INC |
190953 |
0.4% |
| Intrinsic Edge Capital Management LLC |
190000 |
0.4% |
| Bullseye Asset Management LLC |
184820 |
0.3% |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
183613 |
0.3% |
| Engineers Gate Manager LP |
182765 |
0.3% |
| AQR CAPITAL MANAGEMENT LLC |
180059 |
0.3% |
| Assenagon Asset Management S.A. |
166305 |
0.3% |
| JANE STREET GROUP, LLC |
153670 |
0.3% |
| DEUTSCHE BANK AG\ |
143249 |
0.3% |
| TWO SIGMA ADVISERS, LP |
141800 |
0.3% |
| Nuveen Asset Management, LLC |
140477 |
0.3% |
| PRUDENTIAL FINANCIAL INC |
130185 |
0.2% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
121996 |
0.2% |
| Russell Investments Group, Ltd. |
120544 |
0.2% |
| CITADEL ADVISORS LLC |
120501 |
0.2% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
120347 |
0.2% |
| UBS Group AG |
113370 |
0.2% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
112440 |
0.2% |
| LOS ANGELES CAPITAL MANAGEMENT LLC |
111936 |
0.2% |
| SG Americas Securities, LLC |
110416 |
0.2% |
| AMERICAN CENTURY COMPANIES INC |
108366 |
0.2% |
| TWO SIGMA INVESTMENTS, LP |
105980 |
0.2% |
| Invesco Ltd. |
90739 |
0.2% |
| Rafferty Asset Management, LLC |
89434 |
0.2% |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
89351 |
0.2% |
| STATE OF WISCONSIN INVESTMENT BOARD |
87667 |
0.2% |
| RHUMBLINE ADVISERS |
84159 |
0.2% |
| ARS Investment Partners, LLC |
81435 |
0.2% |
| THRIVENT FINANCIAL FOR LUTHERANS |
81331 |
0.2% |
| Jackson Creek Investment Advisors LLC |
75584 |
0.1% |
| Legal & General Group Plc |
70142 |
0.1% |
| FMR LLC |
69320 |
0.1% |
| ALLIANCEBERNSTEIN L.P. |
68050 |
0.1% |
| HRT FINANCIAL LP |
65299 |
0.1% |
| BNP PARIBAS FINANCIAL MARKETS |
64141 |
0.1% |
| ClariVest Asset Management LLC |
64027 |
0.1% |
| MARSHALL WACE, LLP |
55711 |
0.1% |
| Virtus Investment Advisers, Inc. |
55145 |
0.1% |
| EXCHANGE TRADED CONCEPTS, LLC |
51355 |
0.1% |
| Raymond James Financial Services Advisors, Inc. |
49188 |
0.1% |
| BALYASNY ASSET MANAGEMENT L.P. |
48423 |
0.1% |
| FRANKLIN RESOURCES INC |
44236 |
0.1% |
| BARCLAYS PLC |
44023 |
0.1% |
| GUGGENHEIM CAPITAL LLC |
41817 |
0.1% |
| Curi RMB Capital, LLC |
40547 |
0.1% |
| STRS OHIO |
40000 |
0.1% |
| FEDERATED HERMES, INC. |
37003 |
0.1% |
| Brevan Howard Capital Management LP |
36588 |
0.1% |
| LPL Financial LLC |
35666 |
0.1% |
| CITIGROUP INC |
32375 |
0.1% |
| Schonfeld Strategic Advisors LLC |
32246 |
0.1% |
| MetLife Investment Management, LLC |
30344 |
0.1% |
| PRICE T ROWE ASSOCIATES INC /MD/ |
30131 |
0.1% |
| Nebula Research & Development LLC |
29874 |
0.1% |
| Corton Capital Inc. |
29550 |
0.1% |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management |
28163 |
0.1% |
| FOX RUN MANAGEMENT, L.L.C. |
25938 |
48.2‰ |
| VOYA INVESTMENT MANAGEMENT LLC |
24830 |
46.2‰ |
| Boston Partners |
24289 |
45.1‰ |
| JPMORGAN CHASE & CO |
23769 |
44.2‰ |
| Campbell & CO Investment Adviser LLC |
22384 |
41.6‰ |
| Man Group plc |
21860 |
40.6‰ |
| Janney Montgomery Scott LLC |
21463 |
39.9‰ |
| WELLS FARGO & COMPANY/MN |
21214 |
39.4‰ |
| Allspring Global Investments Holdings, LLC |
21164 |
39.3‰ |
| RAYMOND JAMES & ASSOCIATES |
21149 |
39.3‰ |
| TUDOR INVESTMENT CORP ET AL |
20926 |
38.9‰ |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
19281 |
35.8‰ |
