| BlackRock, Inc. |
6869327 |
11.4% |
| BlackRock Finance, Inc. |
6647297 |
11.0% |
| VANGUARD GROUP INC |
6538466 |
10.8% |
| PRICE T ROWE ASSOCIATES INC /MD/ |
5873392 |
9.7% |
| FMR LLC |
4833684 |
8.0% |
| WELLINGTON MANAGEMENT GROUP LLP |
3235555 |
5.4% |
| Rock Springs Capital Management LP |
2460417 |
4.1% |
| STATE STREET CORP |
2379884 |
3.9% |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC |
1593916 |
2.6% |
| GEODE CAPITAL MANAGEMENT, LLC |
1459484 |
2.4% |
| MACQUARIE GROUP LTD |
1312067 |
2.2% |
| JPMORGAN CHASE & CO |
1224654 |
2.0% |
| LORD, ABBETT & CO. LLC |
1190150 |
2.0% |
| ALLIANCEBERNSTEIN L.P. |
1139002 |
1.9% |
| Pictet Asset Management Holding SA |
1127302 |
1.9% |
| Holocene Advisors, LP |
943464 |
1.6% |
| Invesco Ltd. |
932429 |
1.5% |
| ALKEON CAPITAL MANAGEMENT LLC |
893928 |
1.5% |
| Woodline Partners LP |
880147 |
1.5% |
| Polar Capital Holdings Plc |
875000 |
1.5% |
| AMERICAN CENTURY COMPANIES INC |
802733 |
1.3% |
| T. Rowe Price Investment Management, Inc. |
791718 |
1.3% |
| GOLDMAN SACHS GROUP INC |
739238 |
1.2% |
| MILLENNIUM MANAGEMENT LLC |
627626 |
1.0% |
| BROWN ADVISORY INC |
617992 |
1.0% |
| NORGES BANK |
592126 |
1.0% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
546496 |
0.9% |
| NORTHERN TRUST CORP |
543877 |
0.9% |
| Hood River Capital Management LLC |
502820 |
0.8% |
| 1832 Asset Management L.P. |
502651 |
0.8% |
| Point72 Asset Management, L.P. |
501581 |
0.8% |
| MORGAN STANLEY |
421259 |
0.7% |
| BANK OF AMERICA CORP /DE/ |
403696 |
0.7% |
| Man Group plc |
392898 |
0.7% |
| Avidity Partners Management LP |
383000 |
0.6% |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
358255 |
0.6% |
| MARSHALL WACE, LLP |
351756 |
0.6% |
| EMERALD ADVISERS, LLC |
341200 |
0.6% |
| Integral Health Asset Management, LLC |
340000 |
0.6% |
| Nuveen Asset Management, LLC |
339493 |
0.6% |
| Fisher Asset Management, LLC |
336165 |
0.6% |
| Casdin Capital, LLC |
326378 |
0.5% |
| TD ASSET MANAGEMENT INC |
323500 |
0.5% |
| D. E. Shaw & Co., Inc. |
302635 |
0.5% |
| EMERALD MUTUAL FUND ADVISERS TRUST |
278333 |
0.5% |
| Bank of New York Mellon Corp |
273930 |
0.5% |
| VICTORY CAPITAL MANAGEMENT INC |
264995 |
0.4% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
239946 |
0.4% |
| EVENTIDE ASSET MANAGEMENT, LLC |
231685 |
0.4% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
226580 |
0.4% |
| Clearbridge Investments, LLC |
220980 |
0.4% |
| DEUTSCHE BANK AG\ |
220031 |
0.4% |
| JACOBS LEVY EQUITY MANAGEMENT, INC |
190008 |
0.3% |
| EAGLE ASSET MANAGEMENT INC |
188867 |
0.3% |
| FRONTIER CAPITAL MANAGEMENT CO LLC |
185528 |
0.3% |
| First Turn Management, LLC |
184901 |
0.3% |
| Novo Holdings A/S |
175000 |
0.3% |
| VOYA INVESTMENT MANAGEMENT LLC |
172488 |
0.3% |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
169543 |
0.3% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
168759 |
0.3% |
| Assenagon Asset Management S.A. |
165245 |
0.3% |
| AMERIPRISE FINANCIAL INC |
159812 |
0.3% |
| PANAGORA ASSET MANAGEMENT INC |
147564 |
0.2% |
| JANE STREET GROUP, LLC |
142357 |
0.2% |
| Granahan Investment Management, LLC |
139732 |
0.2% |
| Trexquant Investment LP |
133243 |
0.2% |
| Qube Research & Technologies Ltd |
132048 |
0.2% |
| SEGALL BRYANT & HAMILL, LLC |
126954 |
0.2% |
| CITIGROUP INC |
120252 |
0.2% |
| Aquilo Capital Management, LLC |
114600 |
0.2% |
| Swiss National Bank |
114400 |
0.2% |
| RENAISSANCE TECHNOLOGIES LLC |
110400 |
0.2% |
| Orion Investment Co |
108670 |
0.2% |
| DAFNA Capital Management LLC |
104763 |
0.2% |
| Rafferty Asset Management, LLC |
94963 |
0.2% |
| Redmile Group, LLC |
94405 |
0.2% |
| Legal & General Group Plc |
92369 |
0.2% |
| ExodusPoint Capital Management, LP |
91636 |
0.2% |
| RHUMBLINE ADVISERS |
91543 |
0.2% |
| UBS Group AG |
84623 |
0.1% |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
83904 |
0.1% |
| PEREGRINE CAPITAL MANAGEMENT LLC |
79560 |
0.1% |
| AQR CAPITAL MANAGEMENT LLC |
78103 |
0.1% |
| Ally Bridge Group (NY) LLC |
75638 |
0.1% |
| PRUDENTIAL FINANCIAL INC |
74550 |
0.1% |
| BANK OF MONTREAL /CAN/ |
69040 |
0.1% |
| Cinctive Capital Management LP |
67502 |
0.1% |
| ALGERT GLOBAL LLC |
65540 |
0.1% |
| FEDERATED HERMES, INC. |
62354 |
0.1% |
| FIRST TRUST ADVISORS LP |
60138 |
0.1% |
| PRINCIPAL FINANCIAL GROUP INC |
58191 |
0.1% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
57152 |
0.1% |
| Russell Investments Group, Ltd. |
56493 |
0.1% |
| Neuberger Berman Group LLC |
53769 |
0.1% |
| CAPITAL FUND MANAGEMENT S.A. |
53236 |
0.1% |
| BARCLAYS PLC |
53203 |
0.1% |
| SEI INVESTMENTS CO |
52986 |
0.1% |
| Candriam S.C.A. |
52066 |
0.1% |
| STATE OF WISCONSIN INVESTMENT BOARD |
51424 |
0.1% |
| NBW CAPITAL LLC |
51030 |
0.1% |
